GenePage for the aslA gene of Escherichia coli K-12

Primary Gene Name: aslA
EcoGene Accession Number: EG10089
K-12 Gene Accession Number: ECK3794
MG1655 Gene Identifier: b3801
Gene Name Mnemonic: Arylsulfatase-like
Alternate Gene Symbols: atsA; gppB
Description: Predicted periplasmic non-aryl sulfatase, Ser-type; possible periplasmic mucin-desulfating sulfatase
  # bp Upstream # bp Downstream
MW: 60717.60 ---------551 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3984352
Left Intergenic Region

Name: aslB_aslA

Length: 158 bp gap

Orientation: Convergent

Left_end: 3984194

Right_end: 3984351

Centisome: 85.84

Genomic Address
Counterclockwise
Minute or Centisome (%) = 85.84
Right End: 3986007
Right Intergenic Region

Name: aslA_glmZ

Length: 424 bp gap

Orientation: Divergent

Left_end: 3986008

Right_end: 3986431

Centisome: 85.87

E. coli K-12 cells exhibit mucin-desulfating sulfatase activity but not arylsulfatase activity (Yamada, 1978; Jansen, 1999). It is not known if one or both of the predicted periplasmic sulfatases AslA and YdeN are responsible for the observed mucin-desulfating sulfatase activity, but it is possible. AslB is predicted to be the anaerobic sulfatase-maturating enzyme converting Ser136 to 3-oxoalanine in AslA. 3-oxoalanine is also known as Calpha-formylglycine (FGly). The first 24 aa of AslA are predicted to be a type I signal peptide.

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BamHI EcoRI HindIII