GenePage for the bolA gene of Escherichia coli K-12

Primary Gene Name: bolA
EcoGene Accession Number: EG10125
K-12 Gene Accession Number: ECK0429
MG1655 Gene Identifier: b0435
Gene Name Mnemonic: Bolus
Alternate Gene Symbols: None
Description: Stationary-phase morphogene, transcriptional repressor; predicted reductase; regulates mreB, dacA, dacC, and ampC transcription; shape determinant; FtsZ dependent; induced by AI-2 pheromone
  # bp Upstream # bp Downstream
MW: 11993.68 ---------105 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 454472
Left Intergenic Region

Name: yajG_bolA

Length: 304 bp gap

Orientation: Divergent

Left_end: 454168

Right_end: 454471

Centisome: 9.78

Genomic Address
Clockwise
Minute or Centisome (%) = 9.79
Right End: 454789
Right Intergenic Region

Name: bolA_tig

Length: 343 bp gap

Orientation: Codirectional+

Left_end: 454790

Right_end: 455132

Centisome: 9.80

BolA overexpression produces osmotically stable spherical cells. BolA can form a heterodimer in vitro with FeS-bound monothiol glutaredoxin Grx4 but this complex is much less efficient than the FeS-bound Grx4 homodimer in FeS cluster transfer to Fdx (Yeung, 2011). bolA and ibaG(yrbA) are paralogs. BolA and OsmC are distant homologs, although BolA does not have the conserved cysteines of OsmC; BolA is predicted to be a monothiol glutaredoxin-interacting reductase (Huynen, 2005). RpoS regulon.

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BamHI EcoRI HindIII