GenePage for the cstA gene of Escherichia coli K-12

Primary Gene Name: cstA
EcoGene Accession Number: EG10167
K-12 Gene Accession Number: ECK0591
MG1655 Gene Identifier: b0598
Gene Name Mnemonic: Carbon starvation
Alternate Gene Symbols: dppG?; ybdC
Description: Predicted APC superfamily peptide transporter; carbon starvation protein involved in peptide utilization
  # bp Upstream # bp Downstream
MW: 75105.24 ---------701 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 629894
Left Intergenic Region

Name: entH_cstA

Length: 180 bp gap

Orientation: Codirectional+

Left_end: 629714

Right_end: 629893

Centisome: 13.57

Genomic Address
Clockwise
Minute or Centisome (%) = 13.57
Right End: 631999
Right Intergenic Region

Name: cstA_ybdD

Length: 182 bp gap

Orientation: Codirectional+

Left_end: 632000

Right_end: 632181

Centisome: 13.62

cstA opp double mutants grow slower than opp single mutants with tryptone, but not casamino acids, as carbon source (Schultz, 1991). A dppG (originally called dpp) mutation involved in dipeptide transport was mapped near cstA and may be allelic to cstA, with the caveat that a cstA opp double mutant does not display the valyl dipeptide resistance phenotype observed for dpp mutants (Schultz, 1991). Paralogs cstA and yjiY are both in operons with paralogous small proteins of unknown function, ybdD and yjiX, respectively. CstA has an N-terminal CstA domain (PF02554) and a C-terminal CstA-associated DUF4161 domain (PF13722) of unknown function; the CstA domain is a member of the APC clan (CL0062) of APC (Amino acid-Polyamine-organoCation) superfamily transporters.

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BamHI EcoRI HindIII