GenePage for the deaD gene of Escherichia coli K-12

Primary Gene Name: deaD
EcoGene Accession Number: EG10215
K-12 Gene Accession Number: ECK3150
MG1655 Gene Identifier: b3162
Gene Name Mnemonic: DEAD motif
Alternate Gene Symbols: csdA; mssB; rhlD
Description: ATP-dependent RNA helicase, 50S ribosomal subunit biogenesis; translation factor W2; factor X; facilitates translation of mRNAs with 5' secondary structures; multicopy suppressor of rpsB(Ts) mutations
  # bp Upstream # bp Downstream
Verified Start MW: 70546.16 ---------629 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3305971
Left Intergenic Region

Name: mtr_deaD

Length: 153 bp gap

Orientation: Codirectional-

Left_end: 3305818

Right_end: 3305970

Centisome: 71.22

Genomic Address
Counterclockwise
Minute or Centisome (%) = 71.22
Right End: 3307860
Right Intergenic Region

Name: deaD_yrbN

Length: 8 bp overlap

Orientation: Codirectional-

Left_end: 3307853

Right_end: 3307860

Centisome: 71.26

RNA-stimulated ATPase activity and ATP-dependent RNA helciase activities have been demonstrated in vitro for DeaD(CsdA) (Bizebard, 2004). Mechanism of DeaD 50S biogenesis differs from that for SrmB 50S biogenesis. DeaD stabilizes exposed mRNA, possibly by protecting or destabilizing secondary structure of RNase E sites. Cold shock-inducible; acid-inducible.

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BamHI EcoRI HindIII