GenePage for the gltX gene of Escherichia coli K-12

Primary Gene Name: gltX
EcoGene Accession Number: EG10407
K-12 Gene Accession Number: ECK2394
MG1655 Gene Identifier: b2400
Gene Name Mnemonic: Glutamate
Alternate Gene Symbols: None
Description: Glutamate--tRNA ligase
  # bp Upstream # bp Downstream
MW: 53815.73 ---------471 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2519257
Left Intergenic Region

Name: yfeD_gltX

Length: 51 bp gap

Orientation: Convergent

Left_end: 2519206

Right_end: 2519256

Centisome: 54.27

Genomic Address
Counterclockwise
Minute or Centisome (%) = 54.28
Right End: 2520672
Right Intergenic Region

Name: gltX_valU

Length: 258 bp gap

Orientation: Divergent

Left_end: 2520673

Right_end: 2520930

Centisome: 54.31

The zinc binding motif Cys98-x-Cys100-x(24)-Cys125-x-H127 of GltX categorizes this as a SWIM domain (standard C-x-C-x(n)-C-x-H with n=6-25); mutation analysis (C100Y) indicates SWIM plays a minimal role in overall binding of tRNA, but an increased role in orientation of the acceptor 3?-terminal adenosine.

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BamHI EcoRI HindIII