GenePage for the hflX gene of Escherichia coli K-12

Primary Gene Name: hflX
EcoGene Accession Number: EG10437
K-12 Gene Accession Number: ECK4169
MG1655 Gene Identifier: b4173
Gene Name Mnemonic: High frequency lysogenization
Alternate Gene Symbols: hflA; hslX
Description: GTPase, stimulated by 50S subunit binding; role in Mn(2+) homeostasis
  # bp Upstream # bp Downstream
MW: 48327.10 ---------426 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4400672
Left Intergenic Region

Name: hfq_hflX

Length: 75 bp gap

Orientation: Codirectional+

Left_end: 4400597

Right_end: 4400671

Centisome: 94.81

Genomic Address
Clockwise
Minute or Centisome (%) = 94.81
Right End: 4401952
Right Intergenic Region

Name: hflX_hflK

Length: 85 bp gap

Orientation: Codirectional+

Left_end: 4401953

Right_end: 4402037

Centisome: 94.84

hflX mutants are Mn(2+)-sensitive and HflX is involved in Mn(2+) homeostasis (Kaur, 2014). HflX has both GTPase and ATPase activities (Jain, 2009; Dutta, 2009). HflX itself does not affect transposition efficiency and an earlier report of a defect may be due to a polar effect on hflKC (Twiss, 2005; Dutta, 2009).

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BamHI EcoRI HindIII