GenePage for the hycE gene of Escherichia coli K-12

Primary Gene Name: hycE
EcoGene Accession Number: EG10478
K-12 Gene Accession Number: ECK2716
MG1655 Gene Identifier: b2721
Gene Name Mnemonic: Hydrogenase 3
Alternate Gene Symbols: hevE
Description: Hydrogenase 3 large subunit, [NiFe] cluster; heterodimer
  # bp Upstream # bp Downstream
Verified Start MW: 64980.36 ---------569 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2844762
Left Intergenic Region

Name: hycF_hycE

Length: 9 bp gap

Orientation: Codirectional-

Left_end: 2844753

Right_end: 2844761

Centisome: 61.29

Genomic Address
Counterclockwise
Minute or Centisome (%) = 61.29
Right End: 2846471
Right Intergenic Region

Name: hycE_hycD

Length: 17 bp gap

Orientation: Codirectional-

Left_end: 2846472

Right_end: 2846488

Centisome: 61.32

FhlA regulon. Hydrogenase 3 is part of the formate hydrogenlyase complex. Residues 538-569 are removed to form mature protein. Unclipped C-terminus is required for Fe, Ni incorporation. FeNi incorporation is required for C-terminus processing and transport. C-terminal processing causes a conformational change that completes the maturation process.

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BamHI EcoRI HindIII