GenePage for the ftsN gene of Escherichia coli K-12

Primary Gene Name: ftsN
EcoGene Accession Number: EG11529
K-12 Gene Accession Number: ECK3925
MG1655 Gene Identifier: b3933
Gene Name Mnemonic: Filamentation, temperature sensitive
Alternate Gene Symbols: msgA
Description: Cell division and growth; multicopy suppresses ftsA12
  # bp Upstream # bp Downstream
MW: 35793.23 ---------319 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4122380
Left Intergenic Region

Name: hslV_ftsN

Length: 92 bp gap

Orientation: Codirectional-

Left_end: 4122288

Right_end: 4122379

Centisome: 88.81

Genomic Address
Counterclockwise
Minute or Centisome (%) = 88.81
Right End: 4123339
Right Intergenic Region

Name: ftsN_cytR

Length: 91 bp gap

Orientation: Codirectional-

Left_end: 4123340

Right_end: 4123430

Centisome: 88.83

The ftsN gene is essential. Divisome protein. FtsN is a single pass inner membrane protein with a short cytoplasmic N-terminal domain and has a C-terminal periplasmic SPOR domain facilitating binding to the septal ring (Gerding, 2009; Arends, 2010). FtsN has been shown by FRET to directly interact with itself, FtsW, FtsI and ZapA (Alexeeva, 2010). ZapA has been shown by FRET to directly interact with itself, FtsN, FtsZ and FtsI (Alexeeva, 2010).

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BamHI EcoRI HindIII