GenePage for the eamA gene of Escherichia coli K-12

Primary Gene Name: eamA
EcoGene Accession Number: EG11639
K-12 Gene Accession Number: ECK1526
MG1655 Gene Identifier: b1533
Gene Name Mnemonic: Efflux of amino acid metabolites
Alternate Gene Symbols: ydeD
Description: Efflux pump for cysteine and O-acetyl-L-serine; part of a L-cysteine/L-cystine shuttle system confering hydrogen peroxide resistance
  # bp Upstream # bp Downstream
MW: 32324.19 ---------299 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1620238
Left Intergenic Region

Name: marB_eamA

Length: 30 bp gap

Orientation: Convergent

Left_end: 1620208

Right_end: 1620237

Centisome: 34.91

Genomic Address
Counterclockwise
Minute or Centisome (%) = 34.91
Right End: 1621137
Right Intergenic Region

Name: eamA_ydeE

Length: 194 bp gap

Orientation: Divergent

Left_end: 1621138

Right_end: 1621331

Centisome: 34.93

EamA(YdeD) and FliY constitute a L-cysteine/L-cystine shuttle system confering hydrogen peroxide resistance; EamA exports L-cysteine to the periplasm where it scavenges hydrogen peroxide; eamA(ydeD), eamB(yfiK) and fliY are induced by hydrogen peroxide and cysteine (Ohtsu, 2010). EamA belongs to the EamA/RhaT transporter family, DMT superfamily. Dasler et al. used start codon mutagenesis to verify this start codon.

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BamHI EcoRI HindIII