GenePage for the dkgB gene of Escherichia coli K-12

Primary Gene Name: dkgB
EcoGene Accession Number: EG11648
K-12 Gene Accession Number: ECK0207
MG1655 Gene Identifier: b0207
Gene Name Mnemonic: DiKetoGluconate
Alternate Gene Symbols: yafB
Description: 2,5-diketo-D-gluconate reductase B; glyoxal reductase; glyoxal resistance protein
  # bp Upstream # bp Downstream
MW: 29436.79 ---------267 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 229167
Left Intergenic Region

Name: aspU_dkgB

Length: 162 bp gap

Orientation: Codirectional+

Left_end: 229005

Right_end: 229166

Centisome: 4.93

Genomic Address
Clockwise
Minute or Centisome (%) = 4.94
Right End: 229970
Right Intergenic Region

Name: dkgB_yafC

Length: 4 bp overlap

Orientation: Convergent

Left_end: 229967

Right_end: 229970

Centisome: 4.95

DkgB(YafB) has moderate glyoxal reductase activity and weak glycolaldehyde reductase activity; deletion of dkgA(yqhE) increases sensitivity to glyoxal (Lee, 2013). Overexpression of dkgB(yafB) confers glyoxal resistance (Kwon, 2012). 4/32 DkgB(YafB) peptide masses from MS analysis confirm this start codon and indicate that the initial Met is removed (Maillet, 2007).

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BamHI EcoRI HindIII