GenePage for the acpT gene of Escherichia coli K-12

Primary Gene Name: acpT
EcoGene Accession Number: EG12221
K-12 Gene Accession Number: ECK3459
MG1655 Gene Identifier: b3475
Gene Name Mnemonic: Acyl carrier protein
Alternate Gene Symbols: yhhU
Description: 4'-phosphopantetheinyl transferase; CoA-phosphopantetheinyltransferase; multicopy suppressor of acpS1, can modify ACP when overexpressed
  # bp Upstream # bp Downstream
MW: 21767.80 ---------195 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3612969
Left Intergenic Region

Name: yhhT_acpT

Length: 54 bp gap

Orientation: Codirectional+

Left_end: 3612915

Right_end: 3612968

Centisome: 77.84

Genomic Address
Clockwise
Minute or Centisome (%) = 77.84
Right End: 3613556
Right Intergenic Region

Name: acpT_nikA

Length: 110 bp gap

Orientation: Codirectional+

Left_end: 3613557

Right_end: 3613666

Centisome: 77.85

AcpT is related to the Sfp COG2091 branch of the phosphopantetheinyl transferase superfamily; its putative native apo-protein substrate is unknown. A nonsense mutation making a truncated YejM causes increased outer membrane permeability, TS growth, and reduced lipid A synthesis; these phenotypes, and the lethality of a null mutation, are suppressible by a multicopy acpT clone (Hirvas, 1997; De Lay, 2008).

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BamHI EcoRI HindIII