GenePage for the iscX gene of Escherichia coli K-12

Primary Gene Name: iscX
EcoGene Accession Number: EG12311
K-12 Gene Accession Number: ECK2521
MG1655 Gene Identifier: b2524
Gene Name Mnemonic: Iron-sulfur cluster
Alternate Gene Symbols: yfhJ
Description: Fe(2+) donor and activity modulator for cysteine desulfurase
  # bp Upstream # bp Downstream
MW: 7731.57 ---------66 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2656536
Left Intergenic Region

Name: pepB_iscX

Length: 177 bp gap

Orientation: Codirectional-

Left_end: 2656359

Right_end: 2656535

Centisome: 57.23

Genomic Address
Counterclockwise
Minute or Centisome (%) = 57.23
Right End: 2656736
Right Intergenic Region

Name: iscX_fdx

Length: 11 bp gap

Orientation: Codirectional-

Left_end: 2656737

Right_end: 2656747

Centisome: 57.24

IscX serves both as a donor of Fe(2+) and as a regulator of cysteine desulfurase activity during Fe-S cluster assembly (Kim, 2014). Monomeric IscX forms octamers in the presence of iron; IscX binds IscS and both ferric and ferrous iron (Pastore, 2006).

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BamHI EcoRI HindIII