GenePage for the gadC gene of Escherichia coli K-12
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Primary Gene Name: gadC EcoGene Accession Number: EG12456 K-12 Gene Accession Number: ECK1486 MG1655 Gene Identifier: b1492 |
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Gene Name Mnemonic: Glutamic acid decarboxylase Alternate Gene Symbols: acsA; xasA Description: Glutamate-GABA antiporter; glutamate-dependent enzyme, may function in protection against cytoplasmic acidification |
| MW: 55076.67 ---------511 aa |
Pre-Run BlastP UniProt Pre-Run BlastP NR+Env |
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Left End: 1568954 Left Intergenic Region Name: yddW_gadC Length: 130 bp gap Orientation: Codirectional- Left_end: 1568824 Right_end: 1568953 Centisome: 33.80 |
Genomic Address Counterclockwise Minute or Centisome (%) = 33.80 |
Right End: 1570489 Right Intergenic Region Name: gadC_gadB Length: 155 bp gap Orientation: Codirectional- Left_end: 1570490 Right_end: 1570644 Centisome: 33.83 |
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GlsA and GadC form an acid resistance system sufficient to protect E. coli from acid stress in the pressence of glutamine (Lu, 2013). The crystal structure and functional characterization of the E. coli O157:H7 glutamate-gamma-aminobutyric acid antiporter GadC was determined and is identical in sequence to the K-12 enzyme (Ma, 2012). EvgAS regulon.
