GenePage for the adiC gene of Escherichia coli K-12

Primary Gene Name: adiC
EcoGene Accession Number: EG12462
K-12 Gene Accession Number: ECK4108
MG1655 Gene Identifier: b4115
Gene Name Mnemonic: Arginine decarboxylase, induced
Alternate Gene Symbols: aniC(S.t.); yjdD; yjdE
Description: Arginine:agmatine antiporter; arginine-dependent acid resistance; acid-inducible membrane protein
  # bp Upstream # bp Downstream
MW: 46842.62 ---------445 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4335694
Left Intergenic Region

Name: eptA_adiC

Length: 103 bp gap

Orientation: Codirectional-

Left_end: 4335591

Right_end: 4335693

Centisome: 93.41

Genomic Address
Minute or Centisome (%) = 93.41
Right End: 4337031
Right Intergenic Region

Name: adiC_adiY

Length: 136 bp gap

Orientation: Codirectional-

Left_end: 4337032

Right_end: 4337167

Centisome: 93.44

Arg/Agm exchange by Salmonella AdiC in an in vitro reconstituted system was found to be Arg(+)/Agm(2+) exchange, supporting proton pumping (Tsai, 2012; Tsai, 2013). The Salmonella ortholog AniC is induced by anaerobiosis and acid. OtherPDB(S. typhimurium): 3HQK (Lü, 2012). The E. coli AdiC structures (PDB:3H6B,3H5M) are from strain O157:H7 and are 100% identical to the K-12 AdiC sequence (Gao, 2009). EvgAS regulon.

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