GenePage for the gpr gene of Escherichia coli K-12

Primary Gene Name: gpr
EcoGene Accession Number: EG13010
K-12 Gene Accession Number: ECK2995
MG1655 Gene Identifier: b3001
Gene Name Mnemonic: Glyceraldehyde phosphate reductase
Alternate Gene Symbols: mgrA; yghZ
Description: L-glyceraldehyde 3-phosphate reductase, NADPH-dependent; glyoxal and glycolaldehyde reductase; glyoxal resistance protein
  # bp Upstream # bp Downstream
MW: 38832.16 ---------346 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3147897
Left Intergenic Region

Name: yghX_gpr

Length: 205 bp gap

Orientation: Divergent

Left_end: 3147692

Right_end: 3147896

Centisome: 67.81

Genomic Address
Clockwise
Minute or Centisome (%) = 67.82
Right End: 3148937
Right Intergenic Region

Name: gpr_yqhA

Length: 39 bp gap

Orientation: Convergent

Left_end: 3148938

Right_end: 3148976

Centisome: 67.84

Gpr(YghZ) is a heme binding protein, but the heme is not required for Gpr activity (Desai, 2009). Gpr(YghZ) has moderate glyoxal and glycolaldehyde reductase activity and a gpr(yghZ) deletion mutant is glyoxal sensitive (Lee, 2013). Gpr(YghZ) is a weak methylglyoxal reductase and Gpr(YghZ) overexpression confers increased resistance to methylglyoxal. AKR14 family.

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BamHI EcoRI HindIII