GenePage for the casA gene of Escherichia coli K-12

Primary Gene Name: casA
EcoGene Accession Number: EG13119
K-12 Gene Accession Number: ECK2755
MG1655 Gene Identifier: b2760
Gene Name Mnemonic: CRISPR-associated
Alternate Gene Symbols: cse1; ygcL
Description: CRISPR RNA (crRNA) containing Cascade antiviral complex
  # bp Upstream # bp Downstream
MW: 55901.19 ---------502 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2882630
Left Intergenic Region

Name: casB_casA

Length: 8 bp overlap

Orientation: Codirectional-

Left_end: 2882630

Right_end: 2882637

Centisome: 62.10

Genomic Address
Counterclockwise
Minute or Centisome (%) = 62.10
Right End: 2884138
Right Intergenic Region

Name: casA_ygcB

Length: 414 bp gap

Orientation: Codirectional-

Left_end: 2884139

Right_end: 2884552

Centisome: 62.14

The Cascade antiviral complex is comprised of CasABCDE and short CRISPR RNAs (crRNAs) and requires the predicted helicase YgcB(Cas3) for activity (Brouns, 2008). BaeSR regulon. CasA is homologous to human TRRAP protein, phosphatidylinositol kinases and DNA-dependent protein kinases.

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BamHI EcoRI HindIII