GenePage for the glsA gene of Escherichia coli K-12
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Primary Gene Name: glsA EcoGene Accession Number: EG13247 K-12 Gene Accession Number: ECK0479 MG1655 Gene Identifier: b0485 |
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Gene Name Mnemonic: GLutanimaSe Alternate Gene Symbols: glsA1; ybaS Description: Glutaminase 1, GlsA1 |
| MW: 32903.32 ---------310 aa |
Pre-Run BlastP UniProt Pre-Run BlastP NR+Env |
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Left End: 511641 Left Intergenic Region Name: copA_glsA Length: 261 bp gap Orientation: Divergent Left_end: 511380 Right_end: 511640 Centisome: 11.02 |
Genomic Address Clockwise Minute or Centisome (%) = 11.02 |
Right End: 512573 Right Intergenic Region Name: glsA_ybaT Length: 2 bp gap Orientation: Codirectional+ Left_end: 512574 Right_end: 512575 Centisome: 11.04 |
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GlsA and GadC form an acid resistance system sufficient to protect E. coli from acid stress in the pressence of glutamine (Lu, 2013). Early experiments suggesed that GlsA(YbaS) might contribute to acid resistance, as was later demonstrated (Brown, 2008). glsA(ybaS) is in the CueR regulon (Marbach, 2012). glsA(ybaS) may be in the GadE regulon; weak support (Marbach, 2012). Two glutaminases have been purified and biochemically characterized from E. coli B.
