GenePage for the cueR gene of Escherichia coli K-12

Primary Gene Name: cueR
EcoGene Accession Number: EG13256
K-12 Gene Accession Number: ECK0481
MG1655 Gene Identifier: b0487
Gene Name Mnemonic: Cu efflux regulator
Alternate Gene Symbols: ybbI
Description: Activator of copper-responsive regulon genes cueO and copA; MerR homolog
  # bp Upstream # bp Downstream
MW: 15235.16 ---------135 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 513993
Left Intergenic Region

Name: ybaT_cueR

Length: 124 bp gap

Orientation: Codirectional+

Left_end: 513869

Right_end: 513992

Centisome: 11.07

Genomic Address
Clockwise
Minute or Centisome (%) = 11.07
Right End: 514400
Right Intergenic Region

Name: cueR_ybbJ

Length: 0 bp

Orientation: Convergent

Left_end: Null

Right_end: Null

Centisome: 11.08

Although CueR is a soluble copper-binding protein, it was not detected using Cu(I)-MIRAGE, probably because it selectively binds Cu(I), most of which is oxidized to Cu(II) by CueO, and thus the amount of CueR bound to Cu(I) probably lies below the detection limit (Sevcenco, 2009; Sevcenco, 2012).

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BamHI EcoRI HindIII