GenePage for the gmr gene of Escherichia coli K-12

Primary Gene Name: gmr
EcoGene Accession Number: EG13415
K-12 Gene Accession Number: ECK1280
MG1655 Gene Identifier: b1285
Gene Name Mnemonic: Gene modulating RNase II
Alternate Gene Symbols: yciR
Description: Cyclic-di-GMP phosphodiesterase; csgD regulator; modulates protein stability of RNase II; dual domain protein; defective cyclase domain
  # bp Upstream # bp Downstream
MW: 74665.03 ---------661 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1344757
Left Intergenic Region

Name: yciZ_gmr

Length: 147 bp gap

Orientation: Codirectional-

Left_end: 1344610

Right_end: 1344756

Centisome: 28.97

Genomic Address
Counterclockwise
Minute or Centisome (%) = 28.97
Right End: 1346742
Right Intergenic Region

Name: gmr_ymiB

Length: 53 bp gap

Orientation: Divergent

Left_end: 1346743

Right_end: 1346795

Centisome: 29.01

Gmr has an N-terminal PAS signaling domain, a defective diguanylate cyclase domain lacking the I-site (RxxD), then a C-terminal cyclic-di-GMP phosphodiesterase EAL domain. gmr is a non-essential gene. RpoS regulon (Weber, 2006). Gmr(YciR) has cyclic-di-GMP phosphodiesterase activity in vitro (Weber, 2006). YdaM/Gmr(YciR) constitute an RpoS-regulated c-di-GMP synthesis/degradation module inversely regulated by Hns and controlling the expression of curli genes (Weber, 2006).

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BamHI EcoRI HindIII