GenePage for the alaE gene of Escherichia coli K-12

Primary Gene Name: alaE
EcoGene Accession Number: EG13525
K-12 Gene Accession Number: ECK2664
MG1655 Gene Identifier: b2670
Gene Name Mnemonic: Alanine export
Alternate Gene Symbols: ygaW
Description: Alanine exporter, inducible; stress-responsive
  # bp Upstream # bp Downstream
MW: 16949.07 ---------149 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2799164
Left Intergenic Region

Name: stpA_alaE

Length: 668 bp gap

Orientation: Divergent

Left_end: 2798496

Right_end: 2799163

Centisome: 60.29

Genomic Address
Clockwise
Minute or Centisome (%) = 60.31
Right End: 2799613
Right Intergenic Region

Name: alaE_ygaC

Length: 36 bp gap

Orientation: Convergent

Left_end: 2799614

Right_end: 2799649

Centisome: 60.32

The alaE(ygaW) LAX12 and deletion mutant alleles are both sensitive to Ala-Ala; an alaE(ygaW) deletion exports alanine more slowly in the presence of Ala-Ala; overexpressed AlaE(YgaW) complements the alanine export defect of an alaE mutant (Hori, 2011) The AlaE alanine exporter gives the first function to the DUF1144 family, which had not been predicted to be a transporter family.

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BamHI EcoRI HindIII