GenePage for the ecpC gene of Escherichia coli K-12

Primary Gene Name: ecpC
EcoGene Accession Number: EG13563
K-12 Gene Accession Number: ECK0290
MG1655 Gene Identifier: b0291
Gene Name Mnemonic: E. coli common pilus
Alternate Gene Symbols: matD; yagX
Description: Predicted ECP usher outer membrane porin protein; export, assembly and anchoring of ECP; putative EcpBE-EcpC dual chaperone-usher
  # bp Upstream # bp Downstream
MW: 91228.50 ---------841 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 306807
Left Intergenic Region

Name: ecpD_ecpC

Length: 11 bp overlap

Orientation: Codirectional-

Left_end: 306807

Right_end: 306817

Centisome: 6.61

Genomic Address
Minute or Centisome (%) = 6.61
Right End: 309332
Right Intergenic Region

Name: ecpC_ecpB

Length: 25 bp gap

Orientation: Codirectional-

Left_end: 309333

Right_end: 309357

Centisome: 6.66

EcpC is distantly related to the FimD family usher proteins and is the predicted usher protein for ECP(Mat) formation (Pfam PF00577, E = 2.12e-3) (Korea, 2010; Korea, 2011; Garnett, 2012). The O18ac:K1:H7 NMEC ecpRAB(matABC) genes are required for E. coli common pilus (ECP; Mat fimbria) formation when cloned in K-12; (Pouttu, 2001).The E. coli O18ac:K1:H7 NMEC ecpABCDE(matBCDEF) genes are all individually required for E. coli common pilus (ECP) formation in the pathogenic E.coli NMEC strains and ECP production enhances low-temperature biofilm formation in NMEC and and also in K-12 when the silent ecp operon is expressed; ecpR(matA) mRNA was detected in K-12, but not ecpAB(matBC) mRNA (Pouttu, 2001; Lehti, 2010; Garnett, 2012). EcpC contains PPE repeats.

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