GenePage for the flhE gene of Escherichia coli K-12
|
Primary Gene Name: flhE EcoGene Accession Number: EG14013 K-12 Gene Accession Number: ECK1879 MG1655 Gene Identifier: b1878 |
|
|
Gene Name Mnemonic: Flagella Alternate Gene Symbols: None Description: Proton seal during flagellar secretion; periplasmic; bound to flagellar basal body; required for full swarming motility |
| MW: 14059.41 ---------130 aa |
Pre-Run BlastP UniProt Pre-Run BlastP NR+Env |
|
|
Left End: 1962580 Left Intergenic Region Name: yecT_flhE Length: 119 bp gap Orientation: Convergent Left_end: 1962461 Right_end: 1962579 Centisome: 42.28 |
Genomic Address Counterclockwise Minute or Centisome (%) = 42.28 |
Right End: 1962972 Right Intergenic Region Name: flhE_flhA Length: 1 bp overlap Orientation: Codirectional- Left_end: 1962972 Right_end: 1962972 Centisome: 42.29 |
|
E. coli flhE mutant cells grow slowly, are impaired for swarming motility, show filament-dependent cell lysis, and have lower cytoplasmic pH, consistent with a plug or chaperone function for FlhE to prevent protons from leaking into the cell during flagellar secretion (Lee, 2012). The first 16 aa are predicted to be a type I signal peptide; FlhE signal peptide cleavage, periplasmic localization, and basal body association was determined in Salmonella (Lee, 2012).
