GenePage for the cusC gene of Escherichia coli K-12

Primary Gene Name: cusC
EcoGene Accession Number: EG14233
K-12 Gene Accession Number: ECK0564
MG1655 Gene Identifier: b0572
Gene Name Mnemonic: Cu sensor
Alternate Gene Symbols: ibeB; silC(S.t.); ylcB
Description: Silver and copper efflux, OMF lipoprotein component; outer membrane factor (OMF) of a tripartate efflux pump; confers copper and silver resistance; required for invasion of brain microvascular endothelial cells in strain K1
  # bp Upstream # bp Downstream
MW: 50269.59 ---------457 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 595600
Left Intergenic Region

Name: cusR_cusC

Length: 156 bp gap

Orientation: Divergent

Left_end: 595444

Right_end: 595599

Centisome: 12.83

Genomic Address
Clockwise
Minute or Centisome (%) = 12.83
Right End: 596973
Right Intergenic Region

Name: cusC_cusF

Length: 157 bp gap

Orientation: Codirectional+

Left_end: 596974

Right_end: 597130

Centisome: 12.86

cusC is in the cusCFBA Cu/Ag efflux operon regulated by Cu and Ag. TolC, MdtQ, MdtP and CusC are paralogs. The first 17 aa of CusC are a type II signal peptide.

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BamHI EcoRI HindIII