GenePage for the isrC gene of Escherichia coli K-12

Primary Gene Name: isrC
EcoGene Accession Number: EG31150
K-12 Gene Accession Number: ECK1992
MG1655 Gene Identifier: b4435
Gene Name Mnemonic: Intergenic Sequence sRNA
Alternate Gene Symbols: IS102
Description: Novel sRNA, function unknown, CP4-44; flu mRNA 5'UTR; putative prophage remnant
  # bp Upstream # bp Downstream
MW: 62500.36 ---------195 nt Pre-Run BlastN
Left End: 2071317
Left Intergenic Region

Name: yeeP_isrC

Length: 105 bp gap

Orientation: Codirectional+

Left_end: 2071212

Right_end: 2071316

Centisome: 44.62

Genomic Address
Clockwise
Minute or Centisome (%) = 44.62
Right End: 2071511
Right Intergenic Region

Name: isrC_flu

Length: 27 bp gap

Orientation: Codirectional+

Left_end: 2071512

Right_end: 2071538

Centisome: 44.63

The 195 nt isrC sRNA is produced by premature termination of the 222 nt flu(agn43) mRNA 5' UTR; isrC may regulate csrD expression since isrC is complementary to csrD mRNA; the 3' end of isrC has been adjusted to match the 195 nt truncated flu(agn43) 5' UTR (Wallecha, 2014). The start site for isrC has been adjusted to match the precisely mapped start for the flu(agn43) mRNA (Waldron, 2002). isrC RNA was detected at a low level and predicted to be an sRNA (Chen, 2002). No function for the isrC sRNA has yet been experimentally determined and thus it is possible that isrC does not function as an sRNA and is just an attenuated 5' UTR for flu; iscR may be removed as a separate sRNA gene in the future.

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BamHI EcoRI HindIII